Functional characterization oflmo2-Cretransgenic zebrafish

Functional Characterization of Zebrafish (Danio rerio) Bcl10

The complexes formed by BCL10, MALT1 and specific members of the family of CARMA proteins (CBM complex), have recently focused much attention because they represent a central hub regulating activation of the transcription factor NF-κB following various cellular stimulations. In this manuscript, we report the functional characterization of a Danio rerio 241 amino acids polypeptide ortholog of th...

Running head: FUNCTIONAL CHARACTERIZATION OF ZEBRAFISH NHE3B

Na/H and Na/NH4-exchange activities of zebrafish NHE3b expressed in Xenopus oocytes 1 2 Yusuke Ito, Akira Kato, Taku Hirata, Shigehisa Hirose, and Michael F. Romero 3 4 Department of Biological Sciences, Tokyo Institute of Technology, Yokohama, Japan; and 5 Department of Physiology and Biomedical Engineering, Nephrology & Hypertension and O’Brien 6 Urology Research Center, Mayo Clinic College o...

Identification and Functional Characterization of the Zebrafish Gene Quetschkommode (que)

Identification and Functional Characterization of Cardiac Pacemaker Cells in Zebrafish

In the mammalian heart a conduction system of nodes and conducting cells generates and transduces the electrical signals evoking myocardial contractions. Specialized pacemaker cells initiating and controlling cardiac contraction rhythmicity are localized in an anatomically identifiable structure of myocardial origin, the sinus node. We previously showed that in mammalian embryos sinus node cell...

Zebrafish Functional Genomics

Stefan Schulte-Merker has been working with zebra®sh for over ten years and was involved in a number of genetic screens. He was also part of a team that produced a ®rst-generation map of the `Goodfellow panel' of radiation hybrids, which was intended to help in the cloning of the mutated genes. He is currently Head of Fish Genetics at Artemis Pharmaceuticals, in TuÈbingen, who are in the proces...